
Tetrahedron Letters p. 2677 - 2680 (1993)
Update date:2022-08-03
Topics:
Pattenden
Tankard
Cherry
A concise synthetic route to the tricarbonyl subunit (3a) in the immunosuppressant rapamycin (2), based on ruthenium-catalysed oxidation of an acetylenic amide precursor (17) is described, viz (17) → (18) → (20).
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Doi:10.1021/om400773n
(2013)Doi:10.1021/cg300691n
(2012)Doi:10.1039/c7cc05098d
(2017)Doi:10.1021/jm00049a006
(1994)Doi:10.1016/S0040-4039(00)61589-7
(1993)Doi:10.1007/s10593-013-1382-2
(2013)