AURANTIAMIDES: A NEW CLASS OF MODIFIED DIPEPTIDES FROM PIPER AURANTIACUM

Article abstract of DOI:10.1016/0031-9422(81)80116-1

Two new amides, aurantiamide and aurantiamide acetate, were isolated from Piper aurantiacum.Their structures were determined as N-(N'-benzoyl-S-phenylalaninyl)-S-phenylalaninol and its acetate, respectively, from chemical and spectroscopic studies.The structures and stereochemistry were confirmed by synthesis.The corresponding diastereoisomers were also synthesized and their spectroscopic properties compared with those of the natural compounds.Key Word Index- Piper aurantiacum; Piperaceae; seeds; modified dipeptides; aurantiamide, dia-aurantiamide and their acetates.