European Journal of Medicinal Chemistry p. 121 - 126 (1994)
Update date:2022-07-30
Topics:
Law, Ho.
Pera, M. H.
Taillandier, G.
Fatome, M.
Laval, J. D.
Leclerc, G.
Fourteen γ-thiazolidine-1,3-dithiolanes were prepared and tested as radioprotective agents.The combination within a single molecule of thiazolidine and dithiolane moieties, both of which are known for their radioprotective properties, was achieved for the first time.Several molecules show significant radioprotective activity: immediate 4l; delayed 4b, 4f, 4h; or immediate and prolonged 4a. dithiolanes / thiazolidines / radioprotectors / LD50 30 days
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Doi:10.1016/S0040-4039(00)73087-5
(1994)Doi:10.1021/ja00087a021
(1994)Doi:10.1021/acs.orglett.9b01355
(2019)Doi:10.1002/chem.201303006
(2013)Doi:10.1002/ejoc.201301251
(2014)Doi:10.1016/S0040-4039(00)73206-0
(1994)
