Tetrahedron Letters p. 9391 - 9394 (1994)
Update date:2022-07-30
Topics:
Musicki, Branislav
Vevert, Jean-Paul
Syntheses of two conformationally restricted analogues 3 and 4 of the angiotensin II receptor antagonists losartan (1) are described. Michael addition of imidazole-5-carboxaldehyde 8 to biphenylpropiolate 7 provides an efficient method for the skeletal construction of imidazo[1,5-α]pyridine derivatives.
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Doi:10.1002/chem.201304646
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