
Journal of Medicinal Chemistry p. 1884 - 1891 (1995)
Update date:2022-08-03
Topics:
Romines, Karen R.
Watenpaugh, Keith D.
Tomich, Paul K.
Howe, W. Jeffrey
Morris, Jeanette K.
et al.
A unique strategy for the enhancement of secondary binding of an inhibitor to an enzyme has been demonstrated in the design of new human immunodeficiency virus (HIV) protease inhibitors.When the planar benzene ring of a 4-hydroxycoumarin lead compound (1a
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(1967)