Stereoselective Formation of Three Carbon-Carbon Bonds by Cascade Reaction with Enolate Anion: Synthesis of Tricyclo1,6>dodecane and Tricyclo3,8>undecane Derivatives

DOI: 10.1021/jo00099a034

Source and publish data:

Journal of Organic Chemistry p. 6008 - 6013 (1994)

Update date:2022-09-26

Topics: Synthesis Derivatives Cascade reaction Stereoselective

Authors:

Ihara, Masataka

Makita, Kei

Tokunaga, Yuji

Fukumoto, Keiichiro

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00099a034

Reaction of 6-<5(E)-6-(methoxycarbonyl)hex-5-enyl>-2-cyclohexen-1-one (1) with LHMDS, followed by one-pot treatment with CH2O, resulted in a cascade Michael-Michael-aldol reaction, producing hydroxymethylated tricyclo<6.2.2.0^1,6>dodecane 3.The

Full text of DOI:10.1021/jo00099a034

Products guided by the article

Product name:5-<3-(1,3-Dioxacyclohexyl)propyl>-2-methylcyclohexan-1-one

Cas No:165316-61-0

R&D Labs maybe for 165316-61-0

Suzhou Lixin Pharmaceutical Co., Ltd.

Contact:86-512-88169812

Address:21 Tangxi Road, Suzhou New District, Suzhou 215151
Water Chemical Co.,LTD

Contact:+86-21-6856-1349 523-87676172

Address:No16 . BinJiang Road . Taixing Economy Developing Area .JiangSu Province . China
Jitat Company Ltd

Contact:852-27701081

Address:Room 2509, New Tech Plaza, 34 Tai Yau St., San Po Kong, HK
Shanghai Sinofluoro Scientific Co., Ltd

Contact:+86-21-64279360

Address:Room 1006,Building 3,#58 East Xinjian Road, Shanghai ,201100,China,
Jiangsu Institute of Ecomones Co., Ltd

website:http://www.jsmone.com

Contact:+86-519-82821700

Address:95 Huanyuan N. Road, Jintan, Jiangsu, China

Relevant to this article

Carbazol derivatives with antimycobacterial activity

Doi:10.1002/ardp.19943271003
(1994)
Ligand interactions with E-selectin. Identification of a new binding site for recognition of N-acyl aromatic glucosamine substituents of sialyl Lewis X

Doi:10.1021/jm9600611
(1996)
Facile N-arylation of amines and sulfonamides and O-arylation of phenols and arenecarboxylic acids

Doi:10.1021/jo0602221
(2006)
Synthesis, binding properties and theoretical studies of p-tert-butylhexahomotrioxacalix[3]arene tri(adamantyl)ketone with alkali, alkaline earth, transition, heavy metal and lanthanide cations

Doi:10.1016/j.tet.2008.11.005
(2009)
Double Arbuzov Reaction of in Situ Generated Bis(trimethylsiloxy)phosphine with Dielectrophiles: Methodology for the Synthesis of Cyclic Phosphinic Acids

Doi:10.1021/jo00124a018
(1995)
Perhalogenated porphyrinic derivatives with indium and thallium: The X-ray structures of (β-Cl₄TPP)Tl(Cl), (β-Cl₄TPP)In(Cl) and (TpFTPP)Tl(Cl)

Doi:10.1016/j.poly.2004.04.010
(2004)

Article Doi