2-Amino-3-oxohexahydroindolizinoindole-5-carboxylate Derivatives as New Scaffolds for Mimicking β-Turn Secondary Structures. Molecular Dynamics and Stereoselective Synthesis

DOI: 10.1016/0040-4020(95)00402-T

Source and publish data:

Tetrahedron p. 7841 - 7856 (1995)

Update date:2022-09-26

Topics:

Authors:

Figuera, Natalia De la

Alkorta, Ibon

Garcia-Lopez, M. Teresa

Herranz, Rosario

Gonzalez-Muniz, Rosario

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Article abstract of DOI:10.1016/0040-4020(95)00402-T

Highly constrained 2-amino-3-oxohexahydroindolizino<8-7-b>indole-5-carboxylate derivatives of general formula 1 have been developed as novel β-turn mimetics.Molecular dynamics studies on model structures 2a and 2b have revealed that both indolizinoindole

Full text of DOI:10.1016/0040-4020(95)00402-T

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