Synthesis of stable hydroperoxides of sultams by oxidation of isothiazolium salts

Article abstract of DOI:10.1016/0040-4020(95)01037-8

In this paper the first synthesis of stable 3-hydroperoxy-sultams 3a-d as well as the corresponding isothiazol-3(2H)-one 1,1-dioxides 8a-e by oxidation of isothiazolium salts 6a-e is reported. The 3-hydroxy-sultams 7b-d are obtained by reduction of hydroperoxides 3b-d.