First enantioselective synthesis of (-)-(Z)-2,3-methano-L-glutamic acid

DOI: 10.1016/0957-4166(96)00423-5

Source and publish data:

Tetrahedron Asymmetry p. 3203 - 3208 (1996)

Update date:2022-08-02

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Authors:

Jimenez, Jose M.

Ortuno, Rosa M.

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Article abstract of DOI:10.1016/0957-4166(96)00423-5

(-)-(Z)-2,3-Methano-L-glutamic acid, a potential mGluR agonist, has been synthesized for the first time in 40% overall yield from a homochiral amino pentenoate as an easily available precursor. A conveniently protected (-)-(Z)-cyclo-aspartic acid derivati

Full text of DOI:10.1016/0957-4166(96)00423-5

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