Asymmetric induction at two contiguous stereogenic centers by diastereoface differentiating nucleophilic addition reaction

DOI: 10.1016/0040-4039(91)80821-M

Source and publish data:

Tetrahedron Letters p. 3519 - 3522 (1991)

Update date:2022-08-03

Topics:

Authors:

Miyata, Okiko

Shinada, Tetsuro

Ninomiya, Ichiya

Naito, Takeaki

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Article abstract of DOI:10.1016/0040-4039(91)80821-M

Distereoface differentiating nucleophilic of thiophenol to olefins delivers a new concomitant asymmetric construction of two contiguous stereogenic centers and has been successfully applied to the asymmetric synthesis of (+)-diltiazem.

Full text of DOI:10.1016/0040-4039(91)80821-M

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