Enantioselective synthesis of functionalized 2-oxo-cyclohexane carbonitriles. Access to a trioxane analogue of artemisinin

DOI: 10.1016/S0957-4166(97)00238-3

Source and publish data:

Tetrahedron Asymmetry p. 2085 - 2088 (1997)

Update date:2022-08-05

Topics:

Authors:

Hamzaoui

Provot Provot

Gregoire

Riche Riche

Chiaroni

Gay Gay

Moskowitz

Mayrargue

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Article abstract of DOI:10.1016/S0957-4166(97)00238-3

Synthesis of optically active 2-oxo-1-alkylcyclohexane carbonitriles is described leading to access to a new bicyclic simplified analogue of artemisinin.

Full text of DOI:10.1016/S0957-4166(97)00238-3

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Product name:(S)-2-[1-Methoxy-meth-(Z)-ylidene]-1-[2-(2-methyl-[1,3]dithiolan-2-yl)-ethyl]-cyclohexanecarbonitrile

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