Bioorganic and Medicinal Chemistry Letters p. 685 - 690 (1999)
Update date:2022-07-29
Topics:
Rewinkel
Lucas
Van Galen
Noach
Van Dinther
Rood
Jenneboer
Van Boeckel
Replacement of the highly basic benzamidine moiety of NAPAP by the moderately basic 1-aminoisoquinoline moiety resulted in thrombin inhibitors with improved selectivity towards trypsin and enhanced Caco-2 cell permeability.
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Doi:10.1021/jo990212i
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(1990)Doi:10.1021/ol202286q
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(2011)
