Tetrahedron p. 12505 - 12524 (1997)
Update date:2022-08-04
Topics:
Dolle, Valerie
Nguyen, Chi Hung
Bisagni, Emile
In order to obtain 4-C-alkylated pyridin-2(1H)-ones, two strategies were studied: nucleophilic substitution of 4-chloro-3-nitropyridinone derivatives which essentially failed and lithiations of 2-methoxy-3-pivaloylaminopyridines which gave the expected products.
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