A new synthesis of indoloquinolizines by Pictet-Spengler reaction of tryptamine type 1,2-dihydropyridines utilizing sec-nitrodienamine

DOI: 10.1248/cpb.48.1898

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 1898 - 1902 (2000)

Update date:2022-08-04

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Authors:

Koike Koike

Shinohara

Tobinaga

Takeuchi

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Article abstract of DOI:10.1248/cpb.48.1898

The Pictet-Spengler reaction of tryptamine type 1,2-dihydropyridine 5c derived from the cycloaddition of the sec-nitrodienamine 3c with acetaldehyde afforded the indoloquinolizine derivatives 6 and 7.

Full text of DOI:10.1248/cpb.48.1898

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Product name:1-[2-(3-indolyl)ethyl]-2-methyl-3-nitro-1,2-dihydropyridine

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