Russian Chemical Bulletin p. 1121 - 1127 (1999)
Update date:2022-08-03
Topics:
Terent'ev
Vasil'eva
Kuz'mina
Mysov
Ikonnikov
Kuznetsov
Belokon'
Reformatsky-type addition of esters of α-halogeno carboxylic acids to aldehydes and ketones in the presence of Fe(CO)5 and an activating agent (CBrCl3 or I2) afforded the corresponding esters of β-hydroxy acids in good yields. Possible reaction mechanisms are discussed.
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Doi:10.1021/jo991111n
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