NOUVELLE METHODE DE PREPARATION DU 5-HYDROXYMETHYL-2-FURALDEHYDE PAR ACTION DE SELS D'AMMONIUM OU D'IMMONIUM SUR LES MONO-, OLIGO- ET POLY-SACCHARIDES. ACCES DIRECT AUX 5-HALOGENOMETHYL-2-FURALDEHYDES

Article abstract of DOI:10.1016/0008-6215(83)88406-7

In a new and simple process for preparing 5-hydroxymethyl-2-furaldehyde from mono-, oligo- and poly-saccharides, which uses immonium or ammonium salts, direct heating of the reagent and the starting material, both in solid phase, gave directly 5-hydroxymethyl-2-furaldehyde with a good purity, avoiding production of secondary products.The use of a polymeric form of the reagent constitutes an extension of the method toward an eventual industrial application.Under special conditions, a one-pot dehydration-halogenation sequence gave 5-bromomethyl-(or 5-chloromethyl)-2-furaldehyde.