Conjugate addition of diorganozincs to α,β-unsaturated ketones catalyzed by a copper(I)-sulfonamide combined system

Article abstract of DOI:10.1016/0040-4039(96)01038-6

In the presence of a Cu(I)-N-monosubstituted sulfonamide combined catalyst system, diorganozincs react with α,β-unsaturated ketones to generate Zn enolates, which may be hydrolyzed, giving the β-substituted ketones, or used for further aldol reaction or Pd(O)-catalyzed reaction with allyl acetate leading to the regiospecific α,β-vicinal condensation products.