Highly diastereoselective reaction of chiral o-[2-(1,3-oxazolidinyl)]benzaldehydes with alkylmetallic reagents: Synthesis of chiral 3-substituted phthalides

DOI: 10.1248/cpb.39.3136

Source and publish data:

Chemical and Pharmaceutical Bulletin p. 3136 - 3169 (1991)

Update date:2022-08-03

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Authors:

Takahashi

Tsubuki Tsubuki

Higashiyama

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Article abstract of DOI:10.1248/cpb.39.3136

Highly diastereoselective reaction of chiral o-[2-(1,3-oxazolidinyl)]benzaldehydes (4-6) with alkylmetallic reagents provides a new synthetic method for chiral 3-alkylphthalides.

Full text of DOI:10.1248/cpb.39.3136

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