5-Amino-4-(diazoacetyl)-1-β-D-ribofuranosylimidazole, a New Antileukemic Agent

DOI: 10.1021/jm00385a030

Source and publish data:

Journal of Medicinal Chemistry p. 431 - 434 (1987)

Update date:2022-08-05

Topics:

Authors:

Thomas, H. Jeanette

Avery, Lisa N.

Brockman, R. Wallace

Montgomery, John A.

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Article abstract of DOI:10.1021/jm00385a030

5-Amino-4-(diazoacetyl)-1-β-D-ribofuranosylimidazole (15), 5-amino-4-(chloroacetyl)-1-β-D-ribofuranosylimidazole (16), and a number of related imidazole ribonucleosides have been synthesized.Compounds 15 and 16 are cytotoxic to both H.Ep.-2 and L1210 leuk

Full text of DOI:10.1021/jm00385a030

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