Journal of Organic Chemistry p. 2763 - 2766 (1980)
Update date:2022-07-29
Topics:
Degenhardt, Charles R.
A series of new carnitine homologues, 4-hydroxy-5-(trialkylammonio)pentanoates (2) and 5-hydroxy-6-(trialkylammonio)hexanoates (3), has been synthesized.The key step in this synthesis was the reaction of an epoxy ester with a tertiary amine to effect epoxide opening and hydrolysis in one step.The generality of this reaction is discussed, and the synthetic approach to 2 and 3 is compared to previously published routes to carnitine and its analogues.Attempts to apply the new reaction scheme to carnitine itself are described.
View MoreMTT Pharma & Bio-technology Co.,Ltd(expird)
Contact:+86-21-58407925
Address:Room2019, Building C, Tomson Center, No.158, Zhang Yang Road, Shanghai, China
WUXI HONOR SHINE CHEMICAL CO.,LTD
Contact:+86-510-83593312
Address:No.1699 Huishan avenue,Huishan district,Wuxi ,Jiangsu,China,214177.(Wuxi Huishan Ecomonic Develop Zone )
website:http://www.debyesci.com
Contact:+85221376140
Address:Rm. 19C, Lockhart Ctr., 301-307 Lockhart Rd., Wan Chai
website:http://www.josunpharma.com
Contact:+86-311-80715268 80766839
Address:No.39, Zhaiying Street, Shijaizhuang,Hebei,China
Kaymossy BioChem Tech Co., Ltd
website:http://www.kaimosi.com
Contact:0571-87191913/0571-87199097
Address:Room 215, Building 3rd, No.288 Ningxia Road, Qingdao city, China
Doi:10.1016/S0040-4039(01)86511-4
(1979)Doi:10.1021/ja00535a027
(1980)Doi:10.1055/s-2005-865293
(2005)Doi:10.1021/ja0319238
(2004)Doi:10.1016/0040-4020(81)80002-6
(1981)Doi:10.1021/jo01308a002
(1980)
