
Journal of Medicinal Chemistry p. 291 - 294 (1983)
Update date:2022-07-30
Topics:
Piper, James R.
McCaleb, George S.
Montgomery, John A.
Methotrexate poly(γ-L-glutamate)s bearing two and three glutamate units above that present in methotrexate have been synthesized by extension of a previously described route used to synthesize the lower conjugate bearing one added glutamate unit.Key steps
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Doi:10.1021/om00081a036
(1984)Doi:10.1016/S0040-4039(00)87740-0
(1982)Doi:10.1002/jps.2600711108
(1982)Doi:10.1021/ol061256y
(2006)Doi:10.1007/BF00950677
(1982)Doi:10.1021/ja0441007
(2005)