Preparation of some 10-[3-(dimethylamino)-1-propyl] 10H-pyrazino[2,3-b][1,4]benzothiazines as potential neuroleptics

Article abstract of DOI:10.1021/jm00358a020

Chloro- and methyl-substituted 10H-pyrazino[2,3-b][1,4]benzothiazines were prepared and their structures determined by ¹³C NMR and X-ray crystallographic analysis. Alkylation afforded the 10-[3-(dimethylamino)-1-propyl] derivatives, which were