Chemical and Pharmaceutical Bulletin p. 423 - 428 (1983)
Update date:2022-08-03
Topics:
Murakami
Yokoyama
Sasakura
Tamagawa
1,1-disubstituted hydrazines were prepared from the corresponding 1,1-disubstituted ureas by means of the Hofmann rearrangement reaction. The yields were fairly good, except from the ureas susceptible to oxidation, and thus the present method represents an additional and efficient procedure for the synthesis of 1,1-disubstituted hydrazines.
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