Tetrahedron p. 1729 - 1734 (1983)
Update date:2022-08-03
Topics:
El-Wassimy, M.T.M.
Jorgensen, K.A.
Lawesson, S.-O.
The reaction of t-butyl hypochlorite with different thiocarbonyl compounds has been studied.Primary thioamides 1a-c give 1,2,4-thiadiazole derivatives.N-Phenylthiourea 4a gives 5-imino-4-phenyl-3-phenylamino-4,5-dihydro-1,2,4-thiadiazoline 15.Secondary and tertiary thioamides 2a-d, N-methyl-2-thiopyrrolidinone 3, N,N'-dicyclohexylthiourea 4b, N,N,N'-trimethylthiourea 4c, 5-ethyl-5-phenylthiobarbituric acid 5, xanthione 7a, Mischler's thioketone 7b, thiocoumarin 8, O-ethylthiobenzoate 9, O,O-diphenylthiocarbonate 10, di-p-tolyl and o-phenylene trithiocarbonates 11 and 12 have all afforded the oxigen analogues.N,N-Dimethyl-S-phenyldithiocarbonate 6 produces a mixture of di-, tri-, and tetrasulfides.A mechanism for the <*> transformation is suggested in accordance with the Hard and Soft Acids and Bases (HSAB) principle.
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Doi:10.1055/s-2003-42115
(2003)Doi:10.1055/s-2005-870018
(2005)Doi:10.1016/S0040-4039(00)81785-2
(1983)Doi:10.1021/ol052126c
(2005)Doi:10.1021/ja01576a035
(1957)Doi:10.1016/j.bmc.2005.06.054
(2005)