Synthesis of new chiral peptide nucleic acid (PNA) monomers by a simplified reductive amination method

Article abstract of DOI:10.1080/15257779908043081

The aim of this work was the preparation of four new peptide nucleic acid (PNA) monomer backbone by reductive amination of N(α)-Boc-protected chiral amino aldehydes, derived from Leu, Phe, Tyr(Bzl), and Thr(Bzl), with methyl glycinate. To the crude 2-subs

Full text of DOI:10.1080/15257779908043081

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Nucleosides and Nucleotides
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Synthesis of New Chiral Peptide Nucleic
Acid (PNA) Monomers by a Simplified
Reductive Animation Method
Bogdan Falkiewicz a b , Katarzyna Kowalska a , Aleksandra S.
Kolodziejczyk a , Kazimierz Wiśniewski a & Leszek łankiewicz a
a Faculty of Chemistry , University of Gdańsk , Sobieskiego 18,
80-952, Gdańsk
b Department of Biotechnology, Faculty of Biotechnology , University
of Gdańsk and Medical University of Gdańsk , ul. Kladki 24, 80-822,
Gdańsk Fax: E-mail:
Published online: 04 Oct 2006.
To cite this article: Bogdan Falkiewicz , Katarzyna Kowalska , Aleksandra S. Kolodziejczyk , Kazimierz
Wiśniewski & Leszek łankiewicz (1999) Synthesis of New Chiral Peptide Nucleic Acid (PNA) Monomers
by a Simplified Reductive Animation Method, Nucleosides and Nucleotides, 18:3, 353-361, DOI:
10.1080/15257779908043081
To link to this article: http://dx.doi.org/10.1080/15257779908043081
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