Antitrichomonal Activity of Mesoionic Thiazolopyridines

DOI: 10.1021/jm00149a023

Source and publish data:

Journal of Medicinal Chemistry p. 1673 - 1679 (1985)

Update date:2022-08-05

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Authors:

Walker, Keith A. M.

Sjogren, Eric B.

Matthews, Thomas R.

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Article abstract of DOI:10.1021/jm00149a023

Screening of mesoionic compounds as potential electron acceptors by analogy with metronidazole led to the finding of in vitro antitrichomonal activity for anhydro-2-phenyl-3-hydroxythiazolo<3,2-a>pyridinium hydroxide (1).In a series of analogues, potent i

Full text of DOI:10.1021/jm00149a023

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