TRANSFORMATION OF ANDROSTANE DERIVATIVES BY SPIRODELA OLIGORRHIZA

Article abstract of DOI:10.1016/S0031-9422(00)94501-1

Spirodela oligorrhiza (duckweed) of transforming some steroids of the androstane series.Hydrolysis of the acetates of testosterone and of 3-β-hydroxyandrost-5-en-17-one by this species yielded the corresponding alcohols.Further transformation of testosterone and reduction of androst-4-ene-3,17-dione indicated the interconversions of the hyroxy-ketone function on C-17 and redution of the Δ⁴-double bond to the trans-A/B system.Only a trace amount of 3β-hydroxyandrost-5-en-17-one underwent further transformations.