Synthesis and cytotoxicity of analogues of the antibiotic BE 10988 inhibitors of DNA topoisomerase II

DOI: 10.1016/S0960-894X(99)00307-8

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2025 - 2030 (1999)

Update date:2022-08-10

Topics:

Authors:

Catrycke, Marc-Olivier

Houssin, Raymond

Henichart, Jean-Pierre

Pfeiffer, Bruno

Renard, Pierre

Dassonneville, Laurent

Bailly, Christian

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(99)00307-8

Indolequinone derivatives of the antitumour antibiotic BE 10988 were synthesized and evaluated for their cytotoxicity and action mechanism. The quinone system is essential to biological activity and the thiazole ring plays a major role in the poisoning of

Full text of DOI:10.1016/S0960-894X(99)00307-8

Products guided by the article

Product name:3,6-DIMETHOXY-2-NITROBENZALDEHYDE

Cas No:1206-55-9

R&D Labs maybe for 1206-55-9

Chongqing Rong＆Quan Pharmaceutical Technology Co. , Ltd.

Contact:86-023-65268721

Address:No. 7, Manshanhong Village, Pingdingshan, Shapingba District, Chongqing Province, China
Chuzhou Baiao Biologhy S&T Co., Ltd.

Contact:+86-25-83212599；+86-25-83212699 13705185959

Address:Room 905, Tianzheng International Platza, No.399, Zhongyang Road ,Nanjing, Jiangsu Province, China
Jintan Jinnuo Chemical Co., Ltd.

Contact:+86-519-80199901

Address:Room 1804, Building 1, Huacheng Business Plaza, Jintan, Jiangsu, China
xujianqiang

Contact:86-21-57725962

Address:shanghai
Xiamen XM-Innovation Chemical Co., Ltd

Contact:+86-592-3216205

Address:Unit Q, 11/F, No.1 Office Building, Wuyuan Bay Business Center, Huli District, Xiamen City, Fujian Province, P.R.C

Relevant to this article

Invariant sections in ytterbium-indium-soufre crystallographic descriptions of the phases

Doi:10.1016/0025-5408(93)90154-6
(1993)
Molecular recognition of histidine-tagged molecules by metal-chelating lipids monitored by fluorescence energy transfer and correlation spectroscopy

Doi:10.1021/ja9735620
(1998)
Methane oxidation by aqueous osmium tetroxide and sodium periodate: Inhibition of methanol oxidation by methane

Doi:10.1002/anie.200602560
(2006)
Bolaamphiphilic liquid crystals based on bis-imidazolium cations

Doi:10.1039/c6nj03590f
(2017)
Stereospecific photochemistry of Δ²-1,2,3-triazolines in solution and in the solid state: Scope and mechanistic studies

Doi:10.1039/c7pp00187h
(2017)
Electrodeposition of oriented SrCO₃ coatings on stainless steel substrates

Doi:10.1149/1.2188129
(2006)

Article Doi