Synthesis and cytotoxicity of analogues of the antibiotic BE 10988 inhibitors of DNA topoisomerase II

DOI: 10.1016/S0960-894X(99)00307-8

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2025 - 2030 (1999)

Update date:2022-08-10

Topics:

Authors:

Catrycke, Marc-Olivier

Houssin, Raymond

Henichart, Jean-Pierre

Pfeiffer, Bruno

Renard, Pierre

Dassonneville, Laurent

Bailly, Christian

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0960-894X(99)00307-8

Indolequinone derivatives of the antitumour antibiotic BE 10988 were synthesized and evaluated for their cytotoxicity and action mechanism. The quinone system is essential to biological activity and the thiazole ring plays a major role in the poisoning of

Full text of DOI:10.1016/S0960-894X(99)00307-8

Products guided by the article

Product name:3,6-DIMETHOXY-2-NITROBENZALDEHYDE

Cas No:1206-55-9

R&D Labs maybe for 1206-55-9

Shanghai Dano Pharmaceutical Co.,Ld.(expird)

Contact:+86-592-6266840

Address:Building 1 Room 512, 720 Cailun Rd, Zhangjiang High-Tech Park, Shanghai 201203, China
Beijing Pure Chem Co.,Ltd.

Contact:+86-10-83993285

Address:Rm.1708, Haobai Tower, Building 6, No.50, North Road, West Third Ring, Haidian District, Beijing, China
Changzhou LanXu Chemical Co.,ltd.(expird)

Contact:86-0519-86330911,13656129734,15261186386

Address:Room 524, Depart.Chemical, Changzhou Science and Eductaion town, Jiangsu, China;Factory: Haian Fine Chemical Industry Park,Nantong,Jiangsu,China
Beijing Cooperate Pharmaceutical Co.,Ltd

website:http://www.cooperate-pharm.com/

Contact:86-01060279497

Address:No.507,Building 4,Tianhua Street, Biomedicine industrial Base
Jining Shengrun Chemical Industry Co., Ltd.

Contact:+86-537-7121666 ,

Address:West Ring Road,Wenshang County Shandong Province

Relevant to this article

Invariant sections in ytterbium-indium-soufre crystallographic descriptions of the phases

Doi:10.1016/0025-5408(93)90154-6
(1993)
Molecular recognition of histidine-tagged molecules by metal-chelating lipids monitored by fluorescence energy transfer and correlation spectroscopy

Doi:10.1021/ja9735620
(1998)
Methane oxidation by aqueous osmium tetroxide and sodium periodate: Inhibition of methanol oxidation by methane

Doi:10.1002/anie.200602560
(2006)
Bolaamphiphilic liquid crystals based on bis-imidazolium cations

Doi:10.1039/c6nj03590f
(2017)
Stereospecific photochemistry of Δ²-1,2,3-triazolines in solution and in the solid state: Scope and mechanistic studies

Doi:10.1039/c7pp00187h
(2017)
Electrodeposition of oriented SrCO₃ coatings on stainless steel substrates

Doi:10.1149/1.2188129
(2006)

Article Doi