European Journal of Medicinal Chemistry p. 61 - 76 (2018)
Update date:2022-08-29
Topics:
Braun, Florian
Bertoletti, Nicole
M?ller, Gabriele
Adamski, Jerzy
Frotscher, Martin
Guragossian, Nathalie
Madeira Gírio, Patrícia Alexandra
Le Borgne, Marc
Ettouati, Laurent
Falson, Pierre
Müller, Sebastian
Vollmer, Günther
Heine, Andreas
Klebe, Gerhard
Marchais-Oberwinkler, Sandrine
The human enzyme 17β-hydroxysteroid dehydrogenase 14 (17β-HSD14) oxidizes the hydroxyl group at position 17 of estradiol and 5-androstenediol using NAD+ as cofactor. However, the physiological role of the enzyme remains unclear. We recently des
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