Bioorganic and Medicinal Chemistry Letters p. 167 - 172 (1996)
Update date:2022-08-31
Topics:
Derrick, Ian
Moynihan, Humphrey A.
Broadbear, Jillian
Woods, James H.
Lewis, John W.
6N-cinnamoyl-β-naltrexamine and its p-nitro derivative (7 and 8) are κ-opioid agonists of high potency and exceptional efficacy and are only weakly effective μ opioid antagonists. This contrasts with the p-methyl analogue which has only low efficacy κ-ago
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