HYDROXYL-DIRECTED OLEFIN HYDROGENATION WITH IRIDIUM CATALYSTS. THE DOCUMENTATION OF CATALYST : SUBSTRATE STOICHIOMETRY AS A VARIABLE IN REACTION DIASTEREOSELECTION.

Article abstract of DOI:10.1016/S0040-4039(01)91220-1

The present investigation documents the fact that hydroxyl-directed hydrogenation of cyclic and acyclic olefinic alcohols with the cationic iridium catalyst, Ir(COD)py(PCy3)PF6, exhibits reaction diastereoselectivity which is dependent upon catalyst-substrate stoichiometry.