Conformationally constrained ACPD analogues. Synthesis and resolution of 3-aminobicyclo[3,3,0]octane-1,3-dicarboxylic acids

DOI: 10.1016/0040-4020(95)00049-E

Source and publish data:

Tetrahedron p. 3271 - 3278 (1995)

Update date:2022-08-16

Topics:

Authors:

Ezquerra

Ezquerra, Jesus

Yruretagoyena

Yruretagoyena, Belen

Avendano

Avendano, Carmen

De La Cuesta

De La Cuesta, Elena

Gonzalez

Gonzalez, Rosario

Prieto Prieto

Prieto, Lourdes

Pedregal

Pedregal, Carmen

Espada Espada

Espada, Modesta

Prowse Prowse

Prowse, William

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Article abstract of DOI:10.1016/0040-4020(95)00049-E

The synthetic of racemic 3-aminobicyclo[3.3.0]octane-1,3-dicarboxylic acids (2 and 3) which are conformationally constrained ACPD analogues, has been achieved in seven steps starting from the readily available Weiss diketone (4). Partial reduction of 4 to

Full text of DOI:10.1016/0040-4020(95)00049-E

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