CHIMIE DES SUCRES SANS GROUPEMENTS PROTECTEURS-II REACTIONS SELECTIVES D'ADDITION DU D-GLUCOSE, DU D-GALACTOSE ET DE D-GLYCOSYLAMINES A DES HETEROCUMULENES

Article abstract of DOI:10.1016/S0040-4020(01)85430-2

Alkyl isocyanates reacted with 1.5 equivalent of α-methylglucoside, glucose or galactose in pyridine at room temperature, and selectively gave the corresponding 6-N-alkylcarbamates in good yields.The readily available glucosylamine and lactosylamine (1.5-2 eq.) reacted with alkyl isocyanates and isothiocyanates in polar aprotic solvents (pyridine, NMP or DMF), thus affording good yields of the corresponding N-glycosyl N'-alkyl ureas and thioureas.These new sugar derivatives are non-ionic detergents.