Pharmacokinetic and Toxicity Studies

Optimization Purification Data Analysis Structure-Activity Relationship (SAR) Analysis Chemical Synthesis In vitro Testing Biological Assays Structure-Activity Relationship (SAR) Studies Clinical Trials In Vivo Testing Biological Evaluation In Vivo Studies Lead Optimization Lead Compound Selection Preclinical and Clinical Development Regulatory Approval In Vitro Assays Design and Retrosynthetic Analysis Design and Synthesis Animal Models Functional Group Introduction Preclinical and Clinical Trials Design and Rational Drug Discovery Synthesis of Pyrazolone-Pyridazine Conjugates In vivo experiments Iterative Design and Synthesis Patent and Intellectual Property Protection Regulatory Approval and Market Launch Cell-Based Assays Synthesis of 3,5-disubstituted-4-alkynylisoxazoles Synthesis of Oxazinone Ring Linker Attachment Attachment of Pharmacophore Bioassays and Testing Design and Molecular Modeling Further Preclinical Studies