98-50-0

Usage

Uses

Used in Animal Feed Industry:
4-Aminophenylarsonic acid is used as an additive in animal feed for its potential growth-promoting effects. However, its use has been restricted or banned in many countries due to its toxic nature.
Used in Veterinary Medicine:
In the past, 4-Aminophenylarsonic acid was used for treating dysentery in swine. Its chemotherapeutic activity made it a potential candidate for treating certain infections in animals.
Used in Chemical Analysis:
4-Aminophenylarsonic acid has been utilized as a reagent in the determination of zirconium, providing more accurate results in the presence of relatively large amounts of accompanying ions compared to phenylarsonic acid. However, this statement has not yet been confirmed.
Used in Pharmaceutical Industry:
4-Aminophenylarsonic acid is used in the manufacture of medicinal arsenicals, contributing to the development of drugs with chemotherapeutic properties.

Originator

Arsanilic acid,Fleming Laboratories, Inc.

Manufacturing Process

342.0 g (2 mol) of 83% arsenic acid were added during 75 min to a rapidly stirred mixture of 372.5 g (4 mol) aniline and 111.0 g chlorobenzene while the temperature of the mixture was kept at 147°-150°C. After the addition of arsenic acid was complete the mixture was stirred for an additional 8 h while being maintained at 149°-153°C. Water was continuously removed by distillation, and the organic phase of the distillate was continuously recycled back into the reaction mixture. At the end of that time a total of 121.0 g of water, containing the condensation of aniline and arsenic acid has been removed. The mixture was then allowed to cool to 110°C. 562.0 g (2.81 mol) of 20% sodium hydroxide were added over a 2 h period while water, chlorobenzene and excess aniline were distilled off at a temperature of from 102°-113°C. The distillation was continued for an additional 2 h while the volume of the mixture was kept at about 700 ml by the addition of water. The mixture was then diluted with water to a volume of 1400 ml and allowed to cool to 23°C. At this point, 52.0 g of by-product material, which was predominantly tri-(p-aminophenyl)-arsineoxide, were filtered out. The pH of the filtrate was then brought from 8.7 to 5.1 by the addition of 1.8 mol of hydrochloric acid while the volume of the mixture was increased to 2,200 ml by the addition of water. The mixture was stirred for 5 h at room temperature and again filtered. 108.0 g of by-product material comprising predominantly di-(p-aminophenyl)-arsinic acid was filtered off at this point. The pH of the filtrate was lowered to 4.5 by the addition of 0.2 mole of hydrochloric acid, and an additional 5.0 g of by-products, the composition of which was not determined, was filtered off. The filtrate was then brought to a pH of 3.2 by addition of 0.6 mole of hydrochloric acid, and 128.0 g (29.5% based upon arsenic acid) of arsanilic acid were recovered as a precipitate. The arsanilic acid filtrate was combined with the by-products filtered off during each of the three filtration steps. 2.8 mol of hydrochloric acid were added to the combined arsanilic acid filtrate and the mixture was heated at 80°C for 5 days. Arsanilic acid was then precipitated from the remaining hydrolyzed mixture in the manner described for the primary reaction product, and an additional 120.0 g (27.5% based on arsenic acid) were recovered. The filtrate contained 14.0 g (3.2%) of arsanilic acid which could be recovered at least partially in subsequent processing. Thus it can be seen from this example that an arsanilic acid yield of 59% was obtained.

Therapeutic Function

Antibacterial

Hazard

Toxic.

Health Hazard

Occupational workers exposed to p-arsanilic acid develop poisoning. The symptoms include, but are not limited to, eye and skin irritation, chemical conjunctivitis and corneal damage, hyperpigmentation of the skin and, perkeratoses of plantar and palmar surfaces, primary irritation and sensitization, digestive tract irritation, gastrointestinal hypermotility, diarrhea, hepatitis, hepatocellular necrosis, central nervous system depression, cardiac disturbances, and liver and kidney damage. The target organs include the kidneys, central nervous system, liver, and cardiovascular system. After a prolonged period of exposure to arsenic compounds, including arsenical dust, workers are known to develop shortness of breath, nausea, chest pains, garlic odor, and impairment of peripheral circulation. The toxicological properties of p-arsanilic acid have not been fully investigated.

Safety Profile

Poison by intravenous and intraperitoneal routes. Moderately toxic by ingestion. Flammable, decomposes with heat to yield flammable vapors. When heated to decomposition or on contact with acid or acid fumes it emits highly toxic fumes of As and NO,. See also ARSENIC COMPOUNDS and ANILINE.

storage

p-Arsanilic acid should be kept stored in a tightly closed container in a cool, dry, wellventilated area. It should be kept away from incompatible materials, dust generation, excess heat, and strong oxidants.

Purification Methods

Crystallise it from water or ethanol/ether. POISONOUS. [Beilstein 16 I 466.]

Precautions

Occupational workers should wash thoroughly after using p-arsanilic acid. Any contaminated clothing should be washed before reuse. Work areas should have adequate ventilation and minimum dust generation and accumulation. Workers should avoid any kind of contact of p-arsanilic acid with the eyes, skin, clothing, ingestion or inhalation.

InChI:InChI=1/C6H8AsNO3/c8-6-3-1-5(2-4-6)7(9,10)11/h1-4H,8H2,(H2,9,10,11)

Synthetic route

nitarsone (98-72-6) → p-aminophenylarsonic acid (98-50-0)

Conditions	Yield
With sodium hydroxide; hydrogen; palladium under 1520 - 2280 Torr;
With hydrogen; sodium acetate; palladium under 1520 - 2280 Torr;
With sodium hydroxide; iron(II) sulfate
With hydrogenchloride; iron at 85 - 90℃;

anilinium arsenate (63957-41-5) → p-aminophenylarsonic acid (98-50-0)

Conditions	Yield
at 190 - 200℃;

aniline (62-53-3) → p-aminophenylarsonic acid (98-50-0)

Conditions	Yield
at 190 - 200℃; beim Erhitzen von arsensaurem Anilin;

orthoarsenic acid (7778-39-4, 121471-47-4) + aniline (62-53-3) → p-aminophenylarsonic acid (98-50-0) + bis-(4-amino-phenyl)-arsinous acid (857587-34-9)

Conditions	Yield
at 170 - 200℃;

aniline (62-53-3) + arsenic acidic aniline → p-aminophenylarsonic acid (98-50-0) + bis-(4-amino-phenyl)-arsinous acid (857587-34-9)

Conditions	Yield
at 180℃;

4.4'-diamino-arsenobenzene → p-aminophenylarsonic acid (98-50-0)

Conditions	Yield
With dihydrogen peroxide
With iodine; acetic acid

orthoarsenic acid (7778-39-4, 121471-47-4) + aniline (62-53-3) → p-aminophenylarsonic acid (98-50-0)

Conditions	Yield
at 170 - 200℃;

arsenic acidic aniline → p-aminophenylarsonic acid (98-50-0)

Conditions	Yield
at 190 - 200℃;

4-aminophenylarsenoxide (1122-90-3) + iodine (7553-56-2) + acetic acid (64-19-7) → p-aminophenylarsonic acid (98-50-0)

nitarsone (98-72-6) + iron(II) sulfate + furan-2,3,5(4H)-trione pyridine (1:1) → p-aminophenylarsonic acid (98-50-0)

4-aminophenylarsenoxide (1122-90-3) + dihydrogen peroxide (7722-84-1) + alkali → p-aminophenylarsonic acid (98-50-0)

nitarsone (98-72-6) + sodium acetate (127-09-3) + hydrogen + palladium → p-aminophenylarsonic acid (98-50-0)

nitarsone (98-72-6) + furan-2,3,5(4H)-trione pyridine (1:1) + hydrogen + palladium → p-aminophenylarsonic acid (98-50-0)

carbarsone (121-59-5) + furan-2,3,5(4H)-trione pyridine (1:1) → p-aminophenylarsonic acid (98-50-0) + ammonia (7664-41-7) + methylammonium carbonate (15719-64-9, 15719-76-3, 97762-63-5)

Conditions	Yield
Zers.;

N-(4-methoxy-benzoyl)-glycine-(4-arsono-anilide) (860728-63-8) + water (7732-18-5) → p-aminophenylarsonic acid (98-50-0)

Conditions	Yield
Hydrolysis;

[(4-amino-phenyl)-arsanediyldimercapto]-di-acetic acid (31253-24-4) + air → p-aminophenylarsonic acid (98-50-0)

Conditions	Yield
beim Behandeln der alkal. Loesung;

N-(N-ethoxycarbonyl-glycyl)-glycine-(4-arsono-anilide) (857829-92-6) + diluted NaOH-solution → p-aminophenylarsonic acid (98-50-0)

Conditions	Yield
at 85 - 95℃;

orthoarsenic acid (7778-39-4, 121471-47-4) + aniline (62-53-3) → p-aminophenylarsonic acid (98-50-0) + bis-(4-amino-phenyl)-arsinic acid (6309-25-7)

Conditions	Yield
at 170 - 200℃;
In not given at 150°C;; only small amount of (NH2C6H4)2AsO(OH);;
In not given excess of aniline;;
In not given at 150°C;; only small amount of (NH2C6H4)2AsO(OH);;
In not given excess of aniline;;

aniline (62-53-3) + arsenic acidic aniline → p-aminophenylarsonic acid (98-50-0) + bis-(4-amino-phenyl)-arsinic acid (6309-25-7)

Conditions	Yield
at 180℃;

hydrogenchloride (7647-01-0) + bis-(4-amino-phenyl)-arsinic acid (6309-25-7) → p-aminophenylarsonic acid (98-50-0) + aniline (62-53-3)

Conditions	Yield
at 100℃; untersucht wurde die Geschwindigkeit; verschiedener Konzentration.Hydrolysis;
at 130℃; untersucht wurde die Geschwindigkeit; verschiedener Konzentration.Hydrolysis;

p-nitrobenzenediazonium (14368-49-1) → p-aminophenylarsonic acid (98-50-0)

Conditions	Yield
Multi-step reaction with 2 steps 1: alkali; sodium arsenite 2: ferrosulfate; NaOH-solution View Scheme

orthoarsenic acid (7778-39-4, 121471-47-4) + aniline (62-53-3) → p-aminophenylarsonic acid (98-50-0) + C6H5NHAsO(OH)2

Conditions	Yield
In not given heating to 190°C;;	A n/a B 0%
In not given

p-aminophenylarsonic acid (98-50-0) → p-aminophenyldichloroarsine. hydrochloride (5410-78-6)

Conditions	Yield
With hydrogenchloride; sulfur dioxide; potassium iodide In methanol at 20℃; for 0.75h;	98%
With hydrogenchloride; sulfur dioxide; potassium iodide In methanol; water for 0.5h;	95%
With hydrogenchloride; sulfur dioxide; potassium iodide In methanol; water at 0℃; for 0.5h;	93.7%
With hydrogenchloride; sulfur dioxide; potassium iodide In methanol; water at 20℃; for 0.5h;
With hydrogenchloride; sulfur dioxide; potassium iodide In methanol; water

p-aminophenylarsonic acid (98-50-0) + 2-Bromoacetyl bromide (598-21-0) → 4-(N-(bromoacetyl)amino)phenylarsonic acid (51146-91-9)

Conditions	Yield
Stage #1: p-aminophenylarsonic acid With sodium carbonate In water at 4℃; for 2h; Stage #2: 2-Bromoacetyl bromide In dichloromethane; water at 0 - 20℃; for 0.6h; Stage #3: With sulfuric acid; water pH=4;	95%
With sodium carbonate; potassium hydroxide In dichloromethane; water for 0.25h; Cooling with ice;	71.4%
With sodium carbonate In water at 0 - 20℃; for 1.16667h;
With sodium carbonate In water at 0 - 20℃; for 1h; Cooling with ice;

p-aminophenylarsonic acid (98-50-0) → (4-azidophenyl)arsonic acid

Conditions	Yield
Stage #1: p-aminophenylarsonic acid With hydrogenchloride In water at 0℃; for 0.166667h; Stage #2: With sodium nitrite In water at 0℃; for 0.25h; Stage #3: With sodium azide In water at 0 - 20℃; for 12h;	94%

p-aminophenylarsonic acid (98-50-0) + Methacryloyl chloride (920-46-7) → p-methacroloylaminophenylarsonic acid

Conditions	Yield
In ethanol at 4℃; for 2h;	93%

p-aminophenylarsonic acid (98-50-0) + 3-Bromopropionyl chloride (15486-96-1) → 4-(bromopropionamido)-phenylarsanilic acid (636576-17-5)

Conditions	Yield
Stage #1: p-aminophenylarsonic acid With potassium hydroxide; sodium hydrogencarbonate In water Stage #2: 3-Bromopropionyl chloride In water at 0℃; for 0.116667h; Stage #3: With sulfuric acid In water at 0℃; pH=1;	89%

p-aminophenylarsonic acid (98-50-0) + 2-chloropropionyl chloride (625-36-5) → (4-(3-chloropropanamido)phenyl)arsonic acid (74175-13-6)

Conditions	Yield
With sodium carbonate; potassium hydroxide In dichloromethane; water Cooling with ice;	87.58%
Stage #1: p-aminophenylarsonic acid With sodium carbonate; potassium hydroxide In water Cooling with ice; Stage #2: 2-chloropropionyl chloride In dichloromethane; water for 0.333333h; Cooling with ice;	87.58%

p-aminophenylarsonic acid (98-50-0) + undec-10-enoyl chloride (38460-95-6) → C17H26AsNO4

Conditions	Yield
In ethanol for 4h; Cooling with ice;	87%

p-aminophenylarsonic acid (98-50-0) + 6,7-dimethoxy-4-chloroquinazoline (13790-39-1) → 4-(4'-phenylarsonic acid)amino-6,7-dimethoxyquinazoline

Conditions	Yield
With hydrogenchloride In isopropyl alcohol Heating;	85.4%
for 24h; Heating;
With hydrogenchloride In isopropyl alcohol Heating;

p-aminophenylarsonic acid (98-50-0) + [2,2]bipyridinyl (366-18-7) + water (7732-18-5) + copper(II) acetate monohydrate (6046-93-1) + molybdenum(VI) oxide → [{Cu(2,2'-bipyridine)(H2O)}2Mo6O18(O3AsC6H4NH2)2]·3H2O

Conditions	Yield
With ammonium fluoride at 135℃; for 48h; pH=3 - 4; Autoclave;	85%

p-aminophenylarsonic acid (98-50-0) + 4-Chloro-2-methylthiopyrimidine (49844-90-8) → 2-methylthio-4-(4'-aminophenylarsonic acid)aminopyrimidine

Conditions	Yield
With hydrogenchloride In isopropyl alcohol Heating;	82.5%
for 24h; Heating;
With hydrogenchloride In isopropyl alcohol Heating;

p-aminophenylarsonic acid (98-50-0) + sodium metavanadate + water (7732-18-5) + N,N-dimethyl-formamide (68-12-2, 33513-42-7) → Na5[V5O9(4-aminohenylarsonate)4]*20.5H2O*3DMF

Conditions	Yield
With NaN3; N2H4*H2O; HCl In water; N,N-dimethyl-formamide mixt. of NaVO3, NaN3, acid, H2O and DMF was stirred at 70°C untilclear soln. formed; N2H4*H2O, concd. aq. HCl were added at 70°C to pH 7.3; stirred for 15 min; filtered; cooled to room temp.; filtered after 1 d; kept for 2 d;	82%

1.3-propanedithiol (109-80-8) + p-aminophenylarsonic acid (98-50-0) → 2-(4-aminophenyl)-1,3,2-dithiarsinane

Conditions	Yield
Stage #1: p-aminophenylarsonic acid With ammonium 2-sulfanylacetate In ethanol at 55℃; for 1h; Stage #2: 1.3-propanedithiol In ethanol for 0.5h;	80%
Stage #1: p-aminophenylarsonic acid With ammonium 2-sulfanylacetate at 50℃; for 2h; Stage #2: 1.3-propanedithiol	52%
Stage #1: p-aminophenylarsonic acid With ammonium thioglycolate at 50℃; for 2h; Stage #2: 1.3-propanedithiol	52%
Stage #1: p-aminophenylarsonic acid With ammonium 2-sulfanylacetate at 50℃; for 0.5h; Stage #2: 1.3-propanedithiol	35%
Stage #1: p-aminophenylarsonic acid With ammonium 2-sulfanylacetate at 50℃; for 0.5h; Stage #2: 1.3-propanedithiol	35%

p-aminophenylarsonic acid (98-50-0) + [2,2]bipyridinyl (366-18-7) + cobalt(II) diacetate tetrahydrate (6147-53-1) + molybdenum(VI) oxide → [{Co(2,2′-bipyridine)2}2Mo6O18(O3AsC6H4NH2)2]

Conditions	Yield
With ammonium fluoride In water at 135℃; for 48h; pH=4; Autoclave;	75%

p-aminophenylarsonic acid (98-50-0) + allyl bromide (106-95-6) → C12H16AsNO3

Conditions	Yield
With tetrabutylammomium bromide; sodium carbonate In dichloromethane; water at 20℃; for 65h;	75%

p-aminophenylarsonic acid (98-50-0) + 6-chloropurine (87-42-3) → 6-(4'-phenylarsonic acid)aminopurine (17053-73-5)

Conditions	Yield
With hydrogenchloride In isopropyl alcohol Heating;	71.3%
for 24h; Heating;
With hydrogenchloride In isopropyl alcohol Heating;

p-aminophenylarsonic acid (98-50-0) + dihydrolipoic acid (462-20-4) → 2-aminophenyl-4-pentanoic-1,3,2-dithiaarsinane

Conditions	Yield
In methanol for 24h;	71%

p-aminophenylarsonic acid (98-50-0) + lead(II) nitrate → [Pb(4-aminophenylarsonic acid)(NO3)2]

Conditions	Yield
In water at 100℃; for 1h;	71%

p-aminophenylarsonic acid (98-50-0) + N,N-dimethyl-2,3-dihydroxybenzamide (70656-94-9) → bis(2,3,7,8,b,h)-(1NN-dimethylamidobenzo)-5-arsa-5-paraaminophenyl 1,4,6,9-tetraoxaspiro(4,4)nonane (141033-38-7, 141116-18-9, 185951-12-6)

Conditions	Yield
In benzene for 48h; Heating;	70%
In acetic anhydride for 0.333333h; Heating;

p-aminophenylarsonic acid (98-50-0) + N,N-Diethyl-2,3-dihydroxy-benzamide (141033-37-6) → bis(2,3,7,8,b,h)-(1NN-diethylamidobenzo)-5-arsa-5-paraaminophenyl 1,4,6,9-tetraoxaspiro(4,4)nonane (141033-42-3, 141116-22-5, 185951-32-0)

Conditions	Yield
In benzene for 48h; Heating;	70%
In acetic anhydride for 0.333333h; Heating;

p-aminophenylarsonic acid (98-50-0) + succimer (304-55-2) → 2-(4-aminophenyl)-1,3,2-dithiaarsolane-4,5-dicarboxylic acid

Conditions	Yield
Stage #1: p-aminophenylarsonic acid With ammonium 2-sulfanylacetate In ethanol at 55℃; for 1h; Stage #2: succimer In ethanol for 0.5h;	68%

p-aminophenylarsonic acid (98-50-0) + phenol (108-95-2) → 4-(4'-hydroxyphenylazo)phenylarsonic acid (5425-66-1)

Conditions	Yield
	62%

p-aminophenylarsonic acid (98-50-0) + [2,2]bipyridinyl (366-18-7) + zinc(II) acetate dihydrate (5970-45-6) + molybdenum(VI) oxide → [{Zn(2,2′-bipyridine)2}2Mo6O18(O3AsC6H4NH2)2]

Conditions	Yield
With ammonium fluoride In water at 135℃; for 48h; pH=4; Autoclave;	60%

p-aminophenylarsonic acid (98-50-0) + ethane-1,2-dithiol (540-63-6) → 4-(1,3,2-dithiocycloarsenic-2-yl)aniline (5577-20-8)

Conditions	Yield
Stage #1: p-aminophenylarsonic acid With ammonium 2-sulfanylacetate In ethanol at 55℃; for 1h; Stage #2: ethane-1,2-dithiol In ethanol for 0.5h;	60%
Stage #1: p-aminophenylarsonic acid With phenylhydrazine In methanol Reflux; Stage #2: ethane-1,2-dithiol In ethanol for 0.333333h; Reflux;	34%
Stage #1: p-aminophenylarsonic acid With phenylhydrazine In methanol for 1.5h; Reflux; Stage #2: ethane-1,2-dithiol In ethanol for 0.333333h; Reflux;	1.8 g

p-aminophenylarsonic acid (98-50-0) + 2,3-dimercaptopropanol (59-52-9) → (2-(4-aminophenyl)-1,3,2-dithiarsolan-4-yl)methanol

Conditions	Yield
Stage #1: p-aminophenylarsonic acid With ammonium 2-sulfanylacetate at 50℃; for 0.5h; Stage #2: 2,3-dimercaptopropanol	58%

p-aminophenylarsonic acid (98-50-0) + 2,2':6,2''-terpyridine (1148-79-4) + [Cu2(OAc)4(H2O)2] (879089-16-4, 155065-88-6) + water (7732-18-5) + molybdenum(VI) oxide → [(Cu(2,2':6',6''-terpyridine))2Mo4O13H(AsO4)]*2H2O

Conditions	Yield
With H2SO4 In water High Pressure; mixt. of MoO3, Cu acetate, terpyridine, p-arsanilic acid, H2O (mole ratio = 2.51:1.00:1.00:1.25:1253) and concd. H2SO4 stirred briefly, heated at 150°C for 48 h under autogenous pressure; crystals isolated;	55%

p-aminophenylarsonic acid (98-50-0) + silver trifluoromethanesulfonate (2923-28-6) → [Ag(4-aminophenylarsonic acid(-1H))(4-aminophenylarsonic acid)]

Conditions	Yield
With potassium hydroxide In ethanol; water at 100℃; for 1h;	55%

p-aminophenylarsonic acid (98-50-0) + ammonium heptamolybdate tetrahydrate + N,N-dimethyl-formamide (68-12-2, 33513-42-7) → 2NH4(1+)*2H(1+)*(Mo4O8(NH2C6H4AsO3)4)(4-)*HCON(CH3)2*4H2O=(NH4)2H2(Mo4O8(NH2C6H4AsO3)4)*HCON(CH3)2*4H2O

Conditions	Yield
With ammonium acetate; N2H4*H2SO4; acetic acid In water; N,N-dimethyl-formamide to soln. (NH4)6Mo7O24*4H2O and AcONH4 in water-DMF at room temp. N2H4*H2SO4 was added, stirred for 5 min, p-arsanic acid was added, stirred for 10 min, pH was adjusted to 4.9 with aq. AcOH, kept for 5-7 days; elem. anal.;	53%

p-aminophenylarsonic acid (98-50-0) → (4-aminophenyl)arsenous acid

Conditions	Yield
With phenylhydrazine In methanol for 1h; Reflux;	53%
With phenylhydrazine In methanol for 1h; Reflux;	53%
With phenylhydrazine for 2.5h; Reflux;	40%

p-aminophenylarsonic acid (98-50-0) + n-dodecanoyl chloride (112-16-3) → C18H30AsNO4

Conditions	Yield
In ethanol for 4h; Cooling with ice;	51%

p-aminophenylarsonic acid (98-50-0) + [2,2]bipyridinyl (366-18-7) + nickel(II) acetate tetrahydrate (6018-89-9) + molybdenum(VI) oxide → [{Ni(2,2′-bipyridine)2}2Mo6O18(O3AsC6H4NH2)2]

Conditions	Yield
With ammonium fluoride In water at 135℃; for 48h; pH=4; Autoclave;	50%

Upstream product

• 98-72-6 nitarsone 
• 63957-41-5 anilinium arsenate 
• 62-53-3 aniline 
• 7778-39-4 orthoarsenic acid 
• 1122-90-3 4-aminophenylarsenoxide 
• 7553-56-2 iodine 
• 64-19-7 acetic acid 
• 7722-84-1 dihydrogen peroxide 
• 127-09-3 sodium acetate 
• 121-59-5 carbarsone 
• 860728-63-8 N-(4-methoxy-benzoyl)-glycine-(4-arsono-anilide) 
• 7732-18-5 water 
• 31253-24-4 [(4-amino-phenyl)-arsanediyldimercapto]-di-acetic acid 
• 857829-92-6 N-(N-ethoxycarbonyl-glycyl)-glycine-(4-arsono-anilide) 

Downstream Products

• 823813-99-6 [4-(2-hydroxy-ethylamino)-phenyl]-arsonic acid 
• 116532-40-2 (4-[2]furyl-phenyl)-arsonic acid 
• 873983-18-7 [4-(2-bromo-propionylamino)-phenyl]-arsonic acid 
• 97404-78-9 [4-(3-chloro-1,4-dioxo-1,4-dihydro-[2]naphthylamino)-phenyl]-arsonic acid 
• 855885-21-1 (4,4'-ureylene-diphenyl)-bis-arsonic acid 
• 5410-45-7 N-(4-arsonophenyl)glycine 
• 860727-47-5 [(4-amino-phenyl)-arsanediyldimercapto]-di-acetic acid diamide 
• 144-87-6 (4-glycoloylamino-phenyl)-arsonic acid 
• 51112-57-3 (4,4'-thioureylene-diphenyl)-bis-arsonic acid 
• 861301-65-7 [4-(4-methoxy-3-nitro-benzoylamino)-phenyl]-arsonic acid 
• 121-59-5 carbarsone 
• 51112-56-2 (4-arsono-anilino)-methanesulfonic acid 
• 5425-68-3 gluconic acid-(4-arsono-anilide) 
• 119247-75-5 (4-guanidino-phenyl)-arsonic acid 

Relevant academic research and scientific papers

Process for formulating a synthetic drug for use in animal feed, and resulting formulation

A method of formulating a synthetic drug for use in animal feed, for the purpose of reducing carry-over of the synthetic drug to subsequent lots of animal feed in the feed mill.