Highly functionalized diazo compounds (6 and 8)

August 16, 2024

• Title:       

  Highly functionalized diazo compounds (6 and 8)

• Image Source:

  Construction of higly functionalized diazoacetoacentates via catalytic Mukaiyama-Michael reactions

• Mark:

  Scheme 2

• Associated context:

  Herein, we report that highly functionalized diazo compounds (6 and 8) can be prepared by an efficient Lewis acid-catalyzed Mukaiyama-Michael reaction between 1 and enones 5 (Scheme 2) under mild conditions with low catalyst loading of inexpensive zinc triflate.