Welcome to LookChem.com Sign In|Join Free

CAS

  • or

516-05-2

Post Buying Request

516-05-2 Suppliers

Recommended suppliersmore

  • Product
  • FOB Price
  • Min.Order
  • Supply Ability
  • Supplier
  • Contact Supplier

516-05-2 Usage

Chemical Properties

white crystalline powder

Uses

Different sources of media describe the Uses of 516-05-2 differently. You can refer to the following data:
1. 2-Methylpropanedioic acid binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.
2. Methylmalonic acid can be used as a substrate in:Esterification reactions by various catalysts.Synthesis of pyrimidinium betaines with formamidine.Synthesis of malonic acid half thioester (MAHT).

Definition

ChEBI: A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.

Biological Functions

Methylmalonic acid is capable of diffusing out of cells in which it is being produced, so it may be detected in excess in the blood, CSF, and urine of patients with these various forms of the disease.

General Description

Methylmalonic acid is an indicator of vitamin B12 deficiency and methylmalonic acidemia. This Certified Spiking Solution? is suitable for use in preparation of calibrators or controls in clinical and diagnostic testing using GC/MS or LC/MS.

Purification Methods

The acid crystallises as the hydrate from water. [Beilstein 2 IV 1932.]

Check Digit Verification of cas no

The CAS Registry Mumber 516-05-2 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 5,1 and 6 respectively; the second part has 2 digits, 0 and 5 respectively.
Calculate Digit Verification of CAS Registry Number 516-05:
(5*5)+(4*1)+(3*6)+(2*0)+(1*5)=52
52 % 10 = 2
So 516-05-2 is a valid CAS Registry Number.
InChI:InChI=1/C4H6O4/c1-2(3(5)6)4(7)8/h2H,1H3,(H,5,6)(H,7,8)/p-2

516-05-2 Well-known Company Product Price

  • Brand
  • (Code)Product description
  • CAS number
  • Packaging
  • Price
  • Detail
  • Cerilliant

  • (M-080)  Methylmalonicacidsolution  1.0 mg/mL in acetonitrile, ampule of 1 mL, certified reference material

  • 516-05-2

  • M-080-1ML

  • 1,155.96CNY

  • Detail

516-05-2Synthetic route

Diethyl methylmalonate
609-08-5

Diethyl methylmalonate

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With potassium hydroxide In ethanol for 1h; Ambient temperature;99%
With potassium hydroxide In water at 0 - 20℃; for 60h;71%
With potassium hydroxide In ethanol; water for 4h; Heating;
monomethyl monopotassium malonate
38330-80-2

monomethyl monopotassium malonate

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With concentrated hydrochloric acid In water96%
With hydrogenchloride In hexane; dichloromethane84.8%
1,3-di-tert-butyl 2-methylpropanedioate
34812-95-8

1,3-di-tert-butyl 2-methylpropanedioate

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With sodium hydroxide In methanol; dichloromethane at 20℃; for 3h; Solvent;84%
methyl-malonic acid dimethylester
609-02-9

methyl-malonic acid dimethylester

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
In water; toluene81%
With sodium hydroxide In methanol at 20℃;
With water; sodium hydroxide In methanol at 80℃; for 1h;
2-cyanopropanoic acid
632-07-5

2-cyanopropanoic acid

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With potassium hydroxide
2-methylmalonyl dichloride
39619-07-3

2-methylmalonyl dichloride

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With sodium hydroxide
2-methyl-1.3-propanediol
2163-42-0

2-methyl-1.3-propanediol

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With nitric acid
(2RS)-3,3,3-trifluoro-2-methylpropanoic acid
381-97-5

(2RS)-3,3,3-trifluoro-2-methylpropanoic acid

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With sodium hydroxide
2-cyano-3-imino-4-methyl-glutaric acid-1-ethyl ester

2-cyano-3-imino-4-methyl-glutaric acid-1-ethyl ester

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

A

malonic acid
141-82-2

malonic acid

B

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
Kochen;
2-cyano-3-imino-4-methyl-glutaric acid diethyl ester

2-cyano-3-imino-4-methyl-glutaric acid diethyl ester

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

A

malonic acid
141-82-2

malonic acid

B

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

2-cyano-3-imino-2,4,4-trimethyl-glutaric acid diethyl ester

2-cyano-3-imino-2,4,4-trimethyl-glutaric acid diethyl ester

furan-2,3,5(4H)-trione pyridine (1:1)

furan-2,3,5(4H)-trione pyridine (1:1)

A

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

B

2,2-dimethylmalonic acid
595-46-0

2,2-dimethylmalonic acid

Conditions
ConditionsYield
Erhitzen;
methyl-malonyl bromide
98020-11-2

methyl-malonyl bromide

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With water
propionyl chloride
79-03-8

propionyl chloride

trichloromethyl chloroformate
503-38-8

trichloromethyl chloroformate

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
at 225℃; folgendes Verseifen mit Wasser;
at 225℃; im Rohr; und folgende Hydrolyse;
at 225℃; folgendes Verseifen mit Wasser;
potassium cyanide
151-50-8

potassium cyanide

Ethyl 2-bromopropionate
535-11-5, 41978-69-2

Ethyl 2-bromopropionate

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With ethanol ueber mehreren Stufen;
2-methyl-3-oxo-3-(phenylamino)propanoic acid
15601-92-0

2-methyl-3-oxo-3-(phenylamino)propanoic acid

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With sodium hydroxide Heating;
ethene
74-85-1

ethene

carbon dioxide
124-38-9

carbon dioxide

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
1.) Al, AlCl3, methylcyclohexane, 3 atm, 90-95 deg C, 12h; 2.) methylcyclohexane, 75 atm, 80 deg C; Multistep reaction;
malonic acid
141-82-2

malonic acid

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With sodium bromate; sulfuric acid; cerium (IV) sulfate In water at 25℃; Mechanism;
ethyl 2-nitrophenyl methylmalonate
24161-56-6

ethyl 2-nitrophenyl methylmalonate

A

ethanol
64-17-5

ethanol

B

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

C

2-hydroxynitrobenzene
88-75-5

2-hydroxynitrobenzene

Conditions
ConditionsYield
With pH = 8.00 In water at 23℃; under 750.06 Torr; Mechanism; Rate constant; pressure-dependence of rates of elimination; activation parameter for hydrolysis: ΔV(excit.); var. press.;
3,3-Dihydroxy-2-methyl-acrylic acid
69858-40-8

3,3-Dihydroxy-2-methyl-acrylic acid

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With cis-nitrous acid; chloride In water at 25℃; Equilibrium constant;
chloroethane
75-00-3

chloroethane

carbon dioxide
124-38-9

carbon dioxide

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With sodium; Petroleum ether at 110℃; unter Druck;
2-methyl-1.3-propanediol
2163-42-0

2-methyl-1.3-propanediol

nitric acid
7697-37-2

nitric acid

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

carbon dioxide
124-38-9

carbon dioxide

diethylmercury
627-44-1

diethylmercury

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With sodium; Petroleum ether at 110℃; unter Druck;
(2RS)-3,3,3-trifluoro-2-methylpropanoic acid
381-97-5

(2RS)-3,3,3-trifluoro-2-methylpropanoic acid

aqueous NaOH-solution

aqueous NaOH-solution

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

isosuccinic acid amide

isosuccinic acid amide

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
With sodium hydroxide
2-methyl-1.3-propanediol
2163-42-0

2-methyl-1.3-propanediol

KMnO4

KMnO4

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

2-cyano-3-imino-2,4-dimethyl-glutaric acid diethyl ester

2-cyano-3-imino-2,4-dimethyl-glutaric acid diethyl ester

strong KOH-solution

strong KOH-solution

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Conditions
ConditionsYield
Erhitzen;
ethyl 3-bromo-2-(ethoxycarbonyl)propionate
34762-17-9

ethyl 3-bromo-2-(ethoxycarbonyl)propionate

acetic acid
64-19-7

acetic acid

zinc

zinc

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

4-cyano-2-methyl-3-oxo-valeric acid ethyl ester
872822-99-6

4-cyano-2-methyl-3-oxo-valeric acid ethyl ester

alkali, aqueous

alkali, aqueous

A

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

B

propionic acid
802294-64-0

propionic acid

Conditions
ConditionsYield
Hydrolysis;
chloroethane
75-00-3

chloroethane

carbon dioxide
124-38-9

carbon dioxide

sodium

sodium

ligroine

ligroine

A

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

B

propionic acid
802294-64-0

propionic acid

Conditions
ConditionsYield
at 110℃; under 11032.6 Torr;
9-hydroxyxanthene
90-46-0

9-hydroxyxanthene

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

(±)-2-(9H-xanthen-9-yl)propanoic acid
150330-35-1

(±)-2-(9H-xanthen-9-yl)propanoic acid

Conditions
ConditionsYield
With pyrrolidine; isopropyl alcohol; potassium hydroxide In toluene for 24h; Reflux;99%
With pyridine
5-(4'-fluorophenyl)furan-2-carbaldehyde
33342-17-5

5-(4'-fluorophenyl)furan-2-carbaldehyde

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

(E)-2-methyl-3-(5-(4-fluorophenyl)furan-2-yl)acrylic acid

(E)-2-methyl-3-(5-(4-fluorophenyl)furan-2-yl)acrylic acid

Conditions
ConditionsYield
With piperidine; pyridine for 3h; Knoevenagel Condensation; Reflux;96.7%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

disilver methylmalonate

disilver methylmalonate

Conditions
ConditionsYield
With sodium hydroxide; nitric acid; silver nitrate In methanol; water96.7%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

4-(4-methylphenyl)thiophene-2-carbaldehyde
853311-16-7

4-(4-methylphenyl)thiophene-2-carbaldehyde

(E)-2-methyl-3-(4-(4-methylphenyl)thiophen-2-yl)acrylic acid

(E)-2-methyl-3-(4-(4-methylphenyl)thiophen-2-yl)acrylic acid

Conditions
ConditionsYield
With piperidine; pyridine for 3h; Knoevenagel Condensation; Reflux;96.1%
piperidine
110-89-4

piperidine

tert-butyl (+/-)-trans-2,2-dimethyl-3-formylcyclopropanecarboxylate

tert-butyl (+/-)-trans-2,2-dimethyl-3-formylcyclopropanecarboxylate

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

tert-butyl (+/-)-trans-2,2-dimethyl-3-{2-carboxy-(E)-1-propenyl}cyclopropanecarboxylate
1195315-35-5

tert-butyl (+/-)-trans-2,2-dimethyl-3-{2-carboxy-(E)-1-propenyl}cyclopropanecarboxylate

Conditions
ConditionsYield
In pyridine; diethyl ether; hexane; ethyl acetate96%
In pyridine; diethyl ether; hexane; ethyl acetate94.1%
4-phenylthiophene-2-carbaldehyde
26170-87-6

4-phenylthiophene-2-carbaldehyde

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

(E)-2-methyl-3-(4-phenylthiophen-2-yl)acrylic acid
941281-24-9

(E)-2-methyl-3-(4-phenylthiophen-2-yl)acrylic acid

Conditions
ConditionsYield
With piperidine; pyridine for 3h; Knoevenagel Condensation; Reflux;95.5%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

3-methyl-2-methylthio-6-(tetra-O-acetyl-β-D-glucopyranosylamino)pyrimidin-4(3H)-one
94940-17-7

3-methyl-2-methylthio-6-(tetra-O-acetyl-β-D-glucopyranosylamino)pyrimidin-4(3H)-one

3,4,7,8-tetrahydro-5-hydroxy-3,6-dimethyl-2-methylthio-4,7-dioxo-8-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)pyrido<2,3-d>pyrimidine
135112-04-8

3,4,7,8-tetrahydro-5-hydroxy-3,6-dimethyl-2-methylthio-4,7-dioxo-8-(2,3,4,6-tetra-O-acetyl-β-D-glucopyranosyl)pyrido<2,3-d>pyrimidine

Conditions
ConditionsYield
With acetic anhydride at 100℃; for 1h;95%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

di-tert-butyl dicarbonate
24424-99-5

di-tert-butyl dicarbonate

1,3-di-tert-butyl 2-methylpropanedioate
34812-95-8

1,3-di-tert-butyl 2-methylpropanedioate

Conditions
ConditionsYield
With dmap In diethyl ether; tert-butyl alcohol at 23℃; for 48h; Inert atmosphere;95%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

calcium 2-methylmalonate

calcium 2-methylmalonate

Conditions
ConditionsYield
With calcium hydroxide In water at 70℃; for 5h;95%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

allyl alcohol
107-18-6

allyl alcohol

2-methylmalonic acid diallyl ester
150193-37-6

2-methylmalonic acid diallyl ester

Conditions
ConditionsYield
With toluene-4-sulfonic acid In benzene Heating;92%
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 3.08333h;
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

5-(4-tolyl)-2-furaldehyde
34035-05-7

5-(4-tolyl)-2-furaldehyde

(E)-2-methyl-3-(5-(4-methylphenyl)furan-2-yl)acrylic acid

(E)-2-methyl-3-(5-(4-methylphenyl)furan-2-yl)acrylic acid

Conditions
ConditionsYield
With piperidine; pyridine for 3h; Knoevenagel Condensation; Reflux;92%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

4-(4-fluorophenyl)furan-2-carbaldehyde

4-(4-fluorophenyl)furan-2-carbaldehyde

(E)-2-methyl-3-(4-(4-fluorophenyl)furan-2-yl)acrylic acid

(E)-2-methyl-3-(4-(4-fluorophenyl)furan-2-yl)acrylic acid

Conditions
ConditionsYield
With piperidine; pyridine for 3h; Knoevenagel Condensation; Reflux;91.3%
1,2-dimethoxybenzene
91-16-7

1,2-dimethoxybenzene

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

5,6-dimethoxy-2-methyl-1H-indene-1,3(2H)-dione
738616-34-7

5,6-dimethoxy-2-methyl-1H-indene-1,3(2H)-dione

Conditions
ConditionsYield
In dichloromethane at 22℃; for 18h;91%
With Eaton’s reagent In dichloromethane at 22℃; for 18h; Inert atmosphere;66%
1-(2-fluoro-4-iodophenyl)-3-(4-methoxybenzyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione
871700-54-8

1-(2-fluoro-4-iodophenyl)-3-(4-methoxybenzyl)-6-(methylamino)pyrimidine-2,4(1H,3H)-dione

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

1-(2-fluoro-4-iodophenyl)-5-hydroxy-3-(4-methoxybenzyl)-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione
871700-55-9

1-(2-fluoro-4-iodophenyl)-5-hydroxy-3-(4-methoxybenzyl)-6,8-dimethylpyrido[2,3-d]pyrimidine-2,4,7(1H,3H,8H)-trione

Conditions
ConditionsYield
With acetic anhydride at 90 - 100℃; for 4h;90.7%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

4-(3,4-methylene-dioxyphenyl)thiophene-2-carbaldehyde

4-(3,4-methylene-dioxyphenyl)thiophene-2-carbaldehyde

(E)-2-methyl-3-(4-(3,4-methylene-dioxyphenyl)thiophen-2-yl)acrylic acid

(E)-2-methyl-3-(4-(3,4-methylene-dioxyphenyl)thiophen-2-yl)acrylic acid

Conditions
ConditionsYield
With piperidine; pyridine for 3h; Knoevenagel Condensation; Reflux;90.6%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

butan-1-ol
71-36-3

butan-1-ol

dibutyl 2-methylmalonate
52886-83-6

dibutyl 2-methylmalonate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 3.08333h;90%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

isopropyl alcohol
67-63-0

isopropyl alcohol

diisopropyl 2-methylmalonate

diisopropyl 2-methylmalonate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 3.08333h;90%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

cyclohexanol
108-93-0

cyclohexanol

dicyclohexyl 2-methylmalonate
73742-26-4

dicyclohexyl 2-methylmalonate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 3.08333h;90%
2-methoxy-ethanol
109-86-4

2-methoxy-ethanol

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

bis(2-methoxyethyl) 2-methylmalonate

bis(2-methoxyethyl) 2-methylmalonate

Conditions
ConditionsYield
With dmap; dicyclohexyl-carbodiimide In dichloromethane at 0 - 20℃; for 3.08333h;90%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

4-(4-nitrophenyl)thiophene-2-carbaldehyde

4-(4-nitrophenyl)thiophene-2-carbaldehyde

(E)-2-methyl-3-(4-(4-nitrophenyl)thiophen-2-yl)acrylic acid

(E)-2-methyl-3-(4-(4-nitrophenyl)thiophen-2-yl)acrylic acid

Conditions
ConditionsYield
With piperidine; pyridine for 3h; Knoevenagel Condensation; Reflux;89.4%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

2,4,6-Trichlorophenol
88-06-2

2,4,6-Trichlorophenol

bis(2,4,6-trichlorophenyl) 2-methylmalonate
15781-71-2

bis(2,4,6-trichlorophenyl) 2-methylmalonate

Conditions
ConditionsYield
With trichlorophosphate for 5h; Reflux;89.11%
With trichlorophosphate Reflux;
N,N'-dimesitylformamidine
75105-48-5

N,N'-dimesitylformamidine

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

1,3-dimesityl-5-methyl-6-oxo-6H-pyrimidinium-4-olate
1051375-11-1

1,3-dimesityl-5-methyl-6-oxo-6H-pyrimidinium-4-olate

Conditions
ConditionsYield
With dicyclohexyl-carbodiimide In dichloromethane at 20℃; for 3h; Inert atmosphere;89%
With triethylamine; dicyclohexyl-carbodiimide In dichloromethane at 0℃; Schlenk technique; Inert atmosphere;89%
4,4'-bipyridine
553-26-4

4,4'-bipyridine

zinc(II) nitrate hexahydrate

zinc(II) nitrate hexahydrate

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

[Zn2(4,4′-bpy)(Memal)2(H2O)2]n

[Zn2(4,4′-bpy)(Memal)2(H2O)2]n

Conditions
ConditionsYield
With sodium carbonate In methanol; water three parts sepd. by water interphases: aq. soln. of MeCH(CO2H)2 and Na2CO3 at the bottom, soln. of Zn nitrate in the middle region and soln. ofbipyridine in MeOH on the top; sysztem stored at room temp. for a few w k; crystals collected; washed with H2O/EtOH; air dried; elem. anal.;89%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

1,1-di(p-tolyl)ethylene
2919-20-2

1,1-di(p-tolyl)ethylene

2-carboxy-2-methyl-4,4-bis(4-methylphenyl)-4-butanolide

2-carboxy-2-methyl-4,4-bis(4-methylphenyl)-4-butanolide

Conditions
ConditionsYield
With manganese triacetate In acetic acid at 100℃; for 0.05h;88%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

4-(6-fluoropyridin-3-yl)furan-2-carbaldehyde

4-(6-fluoropyridin-3-yl)furan-2-carbaldehyde

(E)-2-methyl-3-(4-(6-fluoropyridin-3-yl)furan-2-yl)acrylic acid

(E)-2-methyl-3-(4-(6-fluoropyridin-3-yl)furan-2-yl)acrylic acid

Conditions
ConditionsYield
With piperidine; pyridine for 3h; Knoevenagel Condensation; Reflux;87.7%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

1,1'-(4-nitro-phenylmethanediyl)-bis-piperidine
55591-35-0

1,1'-(4-nitro-phenylmethanediyl)-bis-piperidine

(E)-2-methyl-3-(4-nitrophenyl)acrylic acid
13048-77-6, 949-98-4, 13048-76-5

(E)-2-methyl-3-(4-nitrophenyl)acrylic acid

Conditions
ConditionsYield
for 96h; Ambient temperature;87%
4,4'-bipyridine
553-26-4

4,4'-bipyridine

cobalt(II) nitrate hexahydrate

cobalt(II) nitrate hexahydrate

methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

[Co(II)2(4,4'-bipyridine)(methylmalonate(2-))2(H2O)2]

[Co(II)2(4,4'-bipyridine)(methylmalonate(2-))2(H2O)2]

Conditions
ConditionsYield
With sodium carbonate In methanol; water three parts sepd. by water interphases: aq. soln. of MeCH(CO2H)2 and Na2CO3 at the bottom, soln. of CoCl2*6H2O in the middle region and soln. ofbipyridine in MeOH on the top; system stored at room temp. for a few wk; crystals collected; washed with H2O/EtOH; air dried; elem. anal.;87%
methyl-propanedioic acid
516-05-2

methyl-propanedioic acid

Acetic acid (2R,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-(2-methoxy-6-oxo-1,6-dihydro-pyrimidin-4-ylamino)-tetrahydro-pyran-3-yl ester
94940-33-7

Acetic acid (2R,3R,4S,5R,6R)-4,5-diacetoxy-6-acetoxymethyl-2-(2-methoxy-6-oxo-1,6-dihydro-pyrimidin-4-ylamino)-tetrahydro-pyran-3-yl ester

4-Acetoxy-3-methyl-7-methoxy-5-(2,3,4,6-tetra-O-acetyl-β-D-glucyopyranosylamino)pyrano<2,3-d>pyrimidin-2-one

4-Acetoxy-3-methyl-7-methoxy-5-(2,3,4,6-tetra-O-acetyl-β-D-glucyopyranosylamino)pyrano<2,3-d>pyrimidin-2-one

Conditions
ConditionsYield
With acetic anhydride at 100℃; for 1h;86%

516-05-2Relevant articles and documents

Heller

, p. 175 (1962)

Biosynthesis of epothilone intermediates with alternate starter units: Engineering polyketide-nonribosomal interfaces

O'Connor, Sarah E.,Walsh, Christopher T.,Liu, Fei

, p. 3917 - 3921 (2003)

The early steps of epothilone biosynthesis were reprogrammed in vitro by incorporating enzyme subunits (e.g. EntB, EntE) from other biosynthetic pathways into the epothilone (Epo) assembly line (see scheme). Recognition sequences identified at the C termini of the epothilone biosynthetic proteins enabled heterologous enzyme transfer when fused to noncognate proteins, as a step toward the reengineering of biosythetic pathways to produce natural product analogues in vivo.

Compounds prepared based on cinnamic acid compounds and capable of promoting germination of parasitic plant seeds and preparation method of compounds prepared based on cinnamic acid compounds

-

Paragraph 0025, (2021/06/22)

The invention discloses compounds prepared on the basis of cinnamic acid compounds and capable of promoting seed germination of parasitic plants and a preparation method of the compounds prepared based on the cinnamic acid compounds, and particularly relates to the technical field of seed germination. The structural general formula of the compounds prepared based on the cinnamic acid compounds is shown in a formula (1), wherein the group R is any one selected from the group consisting of 2-CH3, 3-CH3, 4-CH3, 2,3-CH3, 2,4-CH3, 3,5-CH3, 2-C2H5, 3-C2H5, 4-C2H5, 4-C(CH3)3, 2-OCH3, 3-OCH3, 4-OCH3, 3,4-OCH3, 3,5-OCH3, 2-OC2H5, 3-OC2H5, 4-OC3H7, 2-F, 3-F, 4-F, 2-Cl, 3-Cl, 4-Cl, 2-Br, 3-Br, 4-Br, 2-OCF3-6-Br, 3-OH, 2,3,4-OH, 2-F-3-OCH3, 3-OCH2Ph, 2,5-F, 3-CN, 2-OCH3-5-F, 3,4,5-F, 4-F-3-Cl, 2-CH3-3-F, 2-F-3-Br, 2,5-F, 2,4-F, 3,4-F, 4-OH-3-CH3, 3-CH3-5-CF3, 2,3,4-OCH3, 4-CF3, 4-F-3-Br, 3,5-CF3, 3,4-Cl, 3,4-F, 4,5-OCH3-2-Br and 4-OCH3-3-Br. The compound provided by the invention has the advantage of being capable of promoting seed germination of parasitic plants.

Compound prepared based on indole-3-carboxylic acid and capable of promoting germination of parasitic plant seeds, and preparation method thereof

-

Paragraph 0026, (2021/07/08)

The invention discloses a compound prepared based on indole-3-carboxylic acid and capable of promoting seed germination of parasitic plants, and a preparation method thereof and particularly relates to the technical field of seed germination. The structural general formula of the compound is shown in the formula (1) in the specification. In the formula, the group R is selected from at least one of 4-CH3, 5-CH3, 6-CH3, 7-CH3, 4-F, 5-F, 6-F, 7-F, 4-Cl, 5-Cl, 6-Cl, 7-Cl, 4-Br, 5-Br, 6-Br, 7-Br, 5-NO2, 4-OCH3, 5-OCH3, 5-OH, 5, 6-2F, 5-OCH2Ph, 4, 7-2Cl, 4-C2H5 and 4-OC2H5; and n is equal to 1 or 2 or 3. The compound provided by the invention has the advantage of being capable of promoting germination of striga asiatica seeds.

Post a RFQ

Enter 15 to 2000 letters.Word count: 0 letters

Attach files(File Format: Jpeg, Jpg, Gif, Png, PDF, PPT, Zip, Rar,Word or Excel Maximum File Size: 3MB)

1

What can I do for you?
Get Best Price

Get Best Price for 516-05-2