Total Synthesis of (+/-)-5-O-Methyllicoricidin

DOI: 10.1021/jo00386a024

Source and publish data:

Journal of Organic Chemistry p. 2029 - 2033 (1987)

Update date:2022-07-30

Topics: Total synthesis Chemical Synthesis Starting Materials Natural product Experimental conditions therapeutic properties Organic Molecule

Authors:

Shih, Thomas L.

Wyvratt, Matthew J.

Mrozik, Helmut

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Article abstract of DOI:10.1021/jo00386a024

A novel intramolecular Mitsunobu alkylation is employed to construct the benzopyran moiety of the newly isolated isoflavan 5-O-methyllicoricidin.This convergent 15-step total synthesis outlines a chemically mild approach to the acid-sensitive isoflavanoid

Full text of DOI:10.1021/jo00386a024

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