New Approach to the Synthesis of Deoxyribonucleoside Phosphoramidite Derivatives

Article abstract of DOI:10.1246/cl.1986.1401

The deoxyribonucleoside phosphoramidites with various protecting groups at phosphorus have been prepared rapidly in good yields in one-pot reaction from bis(diisopropylamino)chlorophosphine as a new phosphitylating agent without isolation of bis(diisopropylamino)alkoxyphosphines.