Total Syntheses of Vasicoline and Vasicolinone

DOI: 10.1021/jo00244a007

Source and publish data:

Journal of Organic Chemistry p. 1873 - 1876 (1988)

Update date:2022-08-03

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Authors:

Nakagawa, Yumi

Stevens, Robert V.

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Article abstract of DOI:10.1021/jo00244a007

Bis-ortho-nitration of α-phenyl-N-(phenylmethyl)-γ-butanelactam (6) using acetyl nitrate followed by reduction and regiospecific dehydrative cyclization afforded quinazoline 12.The aniline moiety in 12 could be dimethylated by using aqueous formaldehyde a

Full text of DOI:10.1021/jo00244a007

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Product name:1-(2-nitrobenzyl)-3-(2-nitrophenyl)pyrrolidin-2-one

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