Journal of Medicinal Chemistry p. 63 - 67 (1992)
Update date:2022-07-29
Topics:
Barton, Derek H. R.
Gero, Stephane D.
Lawrence, Francoise
Robert-Gero, Malka
Quiclet-Sire, Beatrice
Samadi, Mohammad
Analogues of sinefungin derivatives 18a and 18b have been prepared from uridine and L-aspartic acid.The key step in the synthesis was the coupling of the radical derived from 14 with the unsaturated amide 13.THe latter was produced from the known N-hydrox
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