Asymmetric Construction of Quaternary Carbons from Chiral Malonates : Total Syntheses of (+)-Epilaurene and (-)-Isolaurene

Article abstract of DOI:10.1016/S0957-4166(00)86009-7

Enantiomerically pure (+)-epilaurene and (-)-isolaurene were obtained from the chiral malonic acid ester (R)-(+)-4, via the 4-methyl-4-p-tolylhex-5-en-1-al (S)-9 prepared by double Wittig reaction under sonication, which underwent subsequent radical induc