Regioselective and Stereoselective Syntheses of 1,2,3-Triaminocyclohexane Derivatives

DOI: 10.1021/jo00067a042

Source and publish data:

Journal of Organic Chemistry p. 4043 - 4048 (1993)

Update date:2022-08-04

Topics:

Authors:

Zhao, Shikai

Freeman, Jeremiah P.

Chidester, Constance G.

VonVoigtlander, Philip F.

Mizsak, Stephen A.

Szmuszkovicz, Jacob

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jo00067a042

The reactions of trans- and cis-3-bromo-1,2-epoxycyclohexanes with pyrrolidine are described.While in the case of the trans-epoxide 2 the amino alcohol 3 was obtained in benzene, the cis-epoxide 5 unexpectedly led to bromo amino alcohol 7 in benzene.Compo

Full text of DOI:10.1021/jo00067a042

Products guided by the article

Product name:trans,trans-2,6-bis(methylamino)-1-pyrrolidinylcyclohexane

Cas No:149405-81-2

R&D Labs maybe for 149405-81-2

suzhou chukai pharmateach co,.ltd

Contact:86-512-88812511

Address:Building 3, Wujiang Scientific Innovation Park, 2358 Changan Rd, Wujiang 215200, Jiangsu Province, P. R. China
Henan Yellow River New Material Technology Co.Ltd.

website:http://www.yellowriverchem.com

Contact:0086-373-7278760

Address:Chengguan Town, Yuanyang County
Guangzhou PI & PI Biotech Inc. Ltd.

Contact:+86-20-81716320

Address:13th Floor, Xinbao Technology Industrial Park, No. 2 Ruixiang Road, Huangpu District, Guangzhou,Guangdong,China
Jiangsu Jiuri Chemical Co.,Ltd.

Contact:+86-519-82118868

Address:Tianwang Town, Jurong City, Jiangsu Province, China
HAORUI ENTERPRISES LLC

Contact:(1) 206-3550089

Address:5115 NE 8TH PL, Renton, WA 98059 USA

Relevant to this article

Diversity-oriented synthesis of fused pyran γ-lactones via an efficient Pd-thiourea-catalyzed alkoxycarbonylative annulation

Doi:10.1021/ol802115u
(2008)
Synthesis and antitumor activities of water-soluble benzoylphenylureas

Doi:10.1248/cpb.47.430
(1999)
Syntheses of acetomycin-related (2R,3S,4R)- and (2S,3R,4R)-2-acetoxy-4- acetyl-3,4-dimethyltetrahydrofuran and their growth inhibition activity against tumor cells

Doi:10.1246/bcsj.66.1441
(1993)
Doi:10.1021/ja01087a024
(1965)
Aldehydes from Nitriles. Formation of N-Alkylnitrilium Ions and Their Reduction to N-Alkylaldimines by Organosilicon Hydrides

Doi:10.1021/jo00316a023
(1981)
O-Demethylation of opioid derivatives with methane sulfonic acid/methionine: Application to the synthesis of naloxone and analogues

Doi:10.1080/00397919208019086
(1992)

Article Doi