European Journal of Medicinal Chemistry p. 715 - 720 (1993)
Update date:2022-09-26
Topics:
Artico, M.
Massa, S.
Santo, R. Di
Costi, R.
Retico, A.
et al.
Various derivatives of 1,2-diaryl-1-(1H-imidazol-1-yl)ethane have been synthesized and tested against Candida albicans and Candida spp.In vitro essays showed chloro and amino derivatives to be as active as miconazole and bifonazole and more potent than ketoconazole.Structure-activity relationships of the new imidazole antifungal agents are discussed.antifungal agents/estrogen-like imidazoles/1,2-diaryl-1-(1H-imidazol-1-yl)ethane derivatives
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Doi:10.1006/bioo.1993.1035
(1993)Doi:10.1021/ja100715e
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