Simple Approach Towards the Synthesis of 5-Methyl-2-hydroxypyrazine Derivatives from Dipeptidyl Chloromethyl Ketones

DOI: 10.1016/0040-4039(94)88031-X

Source and publish data:

Tetrahedron Letters p. 1231 - 1234 (1994)

Update date:2022-08-04

Topics:

Authors:

Okada, Yoshio

Taguchi, Hiroaki

Nishiyama, Yasuhiro

Yokoi, Toshio

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5-Methyl-2-hydroxypyrazine derivatives were easily synthesized by short reflux of dipeptidyl chloromethyl ketone hydrochlorides in MeOH.

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