Helvetica Chimica Acta p. 1278 - 1290 (1995)
Update date:2022-08-04
Topics:
Su
Tamm
A new general concept for the total synthesis of pseurotin A (1), a secondary metabolite of Pseudeurotium ovalis STOLK, which possesses a highly substituted 1-oxa-7-azaspiro[4.4]nonane skeleton, is presented. A key intermediate of the planned reaction sequence is the functionalized γ-lactone 8. The corresponding protected compound 52 was prepared using (S)-O,O-isopropylideneglyceraldehyde (13) and the bromoacetal 14 as starting material. γ-Lactone 52 was obtained in enantiomerically pure state in ten steps. It possesses the desired configuration.
View MoreNanjing Fayekong Chemcial Co.,Ltd(expird)
Contact:86-25-58813444
Address:Rm 1503, Unit 1, Building 5, Zijinnanyuan, Nanjing, Jiangsu, China
Chengdu Pukang Biotechnology Co., Ltd
Contact:+86-28-82550498
Address:No. 558 Rulin Road,Xinjin county,Chengdu city, China
AUSHUN PHARMACEUTICAL TECHNOLOGY CO,.LTD
Contact:+86-25-86883560 15951806178
Address:14 Dayingbi, Zhujiang Rd. East, Nanjing, Jiangsu, China.
Contact:0027-717-456976
Address:2ND FLOOR, 325 VAUSE ROAD, OVERPORT, 4001, SOUTH AFRICA
website:http://www.angchenchem.com
Contact:+86-510-88302099 82327577
Address:Rm. 404/405, Floor 4th, No. 983 FengXiang Road, Wuxi, China
Doi:10.1021/jm00022a015
(1995)Doi:10.1021/ja9531586
(1996)Doi:10.1016/0008-6215(95)00147-L
(1995)Doi:10.1021/acs.orglett.6b02689
(2016)Doi:10.1002/anie.201404352
(2014)Doi:10.1016/0040-4039(95)01674-7
(1995)
