Synthesis of carbohydrate functionalised n-propoxy-Calix[4]arenes

Article abstract of DOI:10.1016/S0040-4039(98)02136-4

The Suzuki reaction has been used to couple para-bromophenyl glycosides to boronic acid derivatives of n-propoxy-Calix[4]arene; 'a one-pot' methodology eliminates the need to isolate the boronic acids and increases the overall yield. The synthesis provides a new class of carbohydrate containing calixarenes with a deepened cavity.