Studies aimed at enhancement of reactivity and enantioselectivity of a lithium ester enolate using a chiral tridentate lithium amide

DOI: 10.1016/S0040-4020(99)00644-4

Source and publish data:

Tetrahedron p. 11219 - 11228 (1999)

Update date:2022-08-04

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Authors:

Hussein, Mostafa Ahmed

Iida, Akira

Tomioka, Kiyoshi

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Article abstract of DOI:10.1016/S0040-4020(99)00644-4

Tridentate chiral amines 7-13 mediated the asymmetric condensation reaction of lithium ester enolate 2 with benzaldehyde p-anisidine imine 3 giving the corresponding β-lactam 4 in up to 75% ee. It became apparent that coexistence of 2 and chiral lithium a

Full text of DOI:10.1016/S0040-4020(99)00644-4

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