One-Pot Conversion of Primary Alkyl Chlorides and Dichlorides into Alcohols, Diols, and Ethers via Formic Ester Intermediates under Phase-Transfer Conditions

Article abstract of DOI:10.1055/s-1986-31769

A procedure for the synthesis of alkyl formates, 1,ω-alkanediyl diformates, and unsaturated analogs from alkyl (or 2-alkenyl) halides and sodium formate under solid/liquid phase-transfer conditions is reported.For conversion into alcohols or diols, respectively, the formic esters can be directly hydrolyzed in the reaction mixture of their preparation.Using a related procedure, cyclic ethers are prepared from 1,ω-dichloroalkanes, sodium formate, and potassium hydroxide under solid/liquid phase-transfer conditions.