
Bulletin of the Chemical Society of Japan p. 1216 - 1220 (1982)
Update date:2022-08-03
Topics:
Ogura, Katasuyuki
Itoh, Hiroshi
Morita, Toshio
Sanada, Kunio
Iida, Hirotada
Starting from alkyl- or aryl-substituted malonic esters prepared by various methods, 2-(methylthio)alkanoic acids are synthesized by successive treatment with sodium ethoxide and with S-methyl methanethiosulfonate, followed by alkaline hydrolysis which causes concurrent decarboxylation.Production of 2-(phenylthio)alkanoic acids is also achieved in a similar manner.
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Doi:10.1021/ja00387a039
(1982)Doi:10.1246/cl.1986.2035
(1986)Doi:10.3390/90600405
(2004)Doi:10.1021/jo048458x
(2005)Doi:10.1002/anie.201508575
(2016)Doi:10.1007/BF00506586
(1982)